The opportunity
Anthropic's Life Sciences team is building a research group focused on biological discoveries by combining AI with hands-on biological research. We're seeking research scientists with deep medicinal chemistry expertise to join the team.
What you'll do
Design multi-step synthetic routes for small molecules and oversee their: execution end to end, including route selection, reaction optimization, purification strategy, and interpretation of full characterization data (NMR, LC-MS, HPLC)
Coordinate synthesis and biological evaluation with external contract: research organizations and academic partners
Evaluate AI-designed molecules and AI-proposed synthetic routes, drive them: to experimental readout, and feed results back to research teams
Apply medicinal chemistry principles, including SAR analysis and: physicochemical property optimization, to compound design and prioritization
Ensure experimental data across programs is high quality and well documented,: including procedures, spectra, and failure modes
Communicate findings clearly to chemistry, AI research, and life sciences audiences
What they're looking for
- + years of medicinal chemistry experience beyond the PhD
- Track record of advancing programs from hit identification through lead optimization
- Experience directing synthetic chemistry activities at contract research organizations
- Computational chemistry, cheminformatics, or coding skills, for example: Python with RDKit or pandas for data analysis and automation
- Experience using AI or ML tools in the life sciences
- Publications and/or patents demonstrating scientific impact